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This original book provides readers with an overview of the latest developments in personalized medicine clinical trials in oncology. The topics covered range from the rationale behind this new generation of clinical trials and the latest statistical models for high-throughput molecular techniques, bioinformatics, high-throughput screening molecular techniques and the challenges entailed by implementing them in daily practice. It also covers the key role of pathology in the validation of molecular results and the complex assessment of predictive biomarkers. The different topics covered are supplemented by unique concrete examples based on the SHIVA trial. The authors are all members of the French Curie Institute, one of the world's foremost cancer research institutions.

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Thông tin chi tiết
Tác giả Christophe le Tourneau,Maud Kamal
Nhà xuất bản Springer International Publishing AG
Năm phát hành 09-2015
ISBN 9783319221885
Trọng lượng (gr) 417
Kích thước 1.0 x 23.0 x 15.0
Số trang 144
Giá bìa 1,500,000 đ